Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for adv...
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
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Author / Creator
SHIVA investigators , Le Tourneau, Christophe, Dr , Delord, Jean-Pierre, Prof , Gonçalves, Anthony, Prof , Gavoille, Céline, MD , Dubot, Coraline, MD , Isambert, Nicolas, MD , Campone, Mario, Prof , Trédan, Olivier, MD , Massiani, Marie-Ange, MD , Mauborgne, Cécile, MSc , Armanet, Sebastien, MSc , Servant, Nicolas, PhD , Bièche, Ivan, PhD , Bernard, Virginie, PhD , Gentien, David, PhD , Jezequel, Pascal, MD , Attignon, Valéry, PhD , Boyault, Sandrine, PhD , Vincent-Salomon, Anne, MD , Servois, Vincent, MD , Sablin, Marie-Paule, MD , Kamal, Maud, PhD and Paoletti, Xavier, PhD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Molecularly targeted agents have been reported to have anti-tumour activity for patients whose tumours harbour the matching molecular alteration. These results have led to increased off-label use of molecularly targeted agents on the basis of identified molecular alterations. We assessed the efficacy of several molecularly target...
Alternative Titles
Full title
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
Authors, Artists and Contributors
Author / Creator
Le Tourneau, Christophe, Dr
Delord, Jean-Pierre, Prof
Gonçalves, Anthony, Prof
Gavoille, Céline, MD
Dubot, Coraline, MD
Isambert, Nicolas, MD
Campone, Mario, Prof
Trédan, Olivier, MD
Massiani, Marie-Ange, MD
Mauborgne, Cécile, MSc
Armanet, Sebastien, MSc
Servant, Nicolas, PhD
Bièche, Ivan, PhD
Bernard, Virginie, PhD
Gentien, David, PhD
Jezequel, Pascal, MD
Attignon, Valéry, PhD
Boyault, Sandrine, PhD
Vincent-Salomon, Anne, MD
Servois, Vincent, MD
Sablin, Marie-Paule, MD
Kamal, Maud, PhD
Paoletti, Xavier, PhD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_02560863v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02560863v1
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(15)00188-6