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BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02633594v1

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

About this item

Full title

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

Publisher

Public Library of Science

Journal title

PloS one, 2014, Vol.9 (7)

Language

English

Formats

Publication information

Publisher

Public Library of Science

Subjects

More information

Scope and Contents

Contents

The hypermetabolic nature of cancer cells and their increased reliance on "aerobic glycolysis'', as originally described by Otto Warburg and colleagues, are considered metabolic hallmarks of cancer cells. BRCA1 is a major tumor suppressor in breast cancer and it was implicated in numerous pathways resulting in anticarcinogenic functions. The object...

Alternative Titles

Full title

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_02633594v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02633594v1

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0102438

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