Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
About this item
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Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
The intestinal epithelium functions to absorb nutrients and to protect the organism against microbes. To prevent autoimmune attack on this vital tissue, T cell tolerance to intestinal self-antigens must be established. Central tolerance mechanisms involve medullary thymic epithelial cells (mTECs), which use endogenously expressed peripheral-tissue...
Alternative Titles
Full title
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_02662332v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02662332v1
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916,1365-2567
DOI
10.1038/ni1427
