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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02680432v1

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

About this item

Full title

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Publisher

Nature Publishing Group

Journal title

Nature (London), 2003, Vol.421 (6919), p.182-187

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

Subjects

More information

Scope and Contents

Contents

Studies in invertebrates have led to the identification of a number of genes that regulate lifespan, some of which encode components of the insulin or insulin-like signalling pathways. Examples include the related tyrosine kinase receptors InR (Drosophila melanogaster) and DAF-2 (Caenorhabditis elegans) that are homologues of the mammalian insulin-...

Alternative Titles

Full title

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_02680432v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02680432v1

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature01298

How to access this item