Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrime...
Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector
About this item
Full title
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Publisher
England: Future Medicine Ltd
Journal title
Language
English
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Publication information
Publisher
England: Future Medicine Ltd
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Scope and Contents
Contents
Alterations of microglia, the brain-resident macrophages, are associated with numerous brain pathologies. Genetic manipulation of microglia in diseases using small interfering RNA (siRNA) is hampered by the lack of safe and efficient siRNA delivery methods. We assessed the amphiphilic dendrimer (AD) for functional siRNA delivery and gene knockdown...
Alternative Titles
Full title
Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector
Authors, Artists and Contributors
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_02992806v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02992806v1
Other Identifiers
ISSN
1743-5889
E-ISSN
1748-6963
DOI
10.2217/nnm-2019-0176
