A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy
A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy
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Author / Creator
Publisher
Cell Press
Journal title
Language
English
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Publication information
Publisher
Cell Press
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Scope and Contents
Contents
The industrial development of active immunotherapy based on live-attenuated bacterial vectors has matured. We developed a microsyringe for antigen delivery based on the type III secretion system (T3SS) of P. aeruginosa. We applied the "killed but metabolically active" (KBMA) attenuation strategy to make this bacterial vector suitable for human use....
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Full title
A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03021548v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03021548v1
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2013.41