Log in to save to my catalogue

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03021548v1

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy

About this item

Full title

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy

Publisher

Cell Press

Journal title

Molecular therapy, 2013-05, Vol.21 (5), p.1076-86

Language

English

Formats

Publication information

Publisher

Cell Press

More information

Scope and Contents

Contents

The industrial development of active immunotherapy based on live-attenuated bacterial vectors has matured. We developed a microsyringe for antigen delivery based on the type III secretion system (T3SS) of P. aeruginosa. We applied the "killed but metabolically active" (KBMA) attenuation strategy to make this bacterial vector suitable for human use....

Alternative Titles

Full title

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03021548v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03021548v1

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1038/mt.2013.41

How to access this item