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An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safet...

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03041310v1

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile

About this item

Full title

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile

Publisher

Beijing: Tsinghua University Press

Journal title

Nano research, 2021-07, Vol.14 (7), p.2247-2254

Language

English

Formats

Publication information

Publisher

Beijing: Tsinghua University Press

More information

Scope and Contents

Contents

Gene therapy using small interfering RNA (siRNA) is emerging as a novel therapeutic approach to treat various diseases. However, safe and efficient siRNA delivery still constitutes the major obstacle for clinical implementation of siRNA therapeutics. Here we report an ionizable supramolecular dendrimer vector, formed via self-assembly of a small am...

Alternative Titles

Full title

An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03041310v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03041310v1

Other Identifiers

ISSN

1998-0124

E-ISSN

1998-0000

DOI

10.1007/s12274-020-3216-8

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