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Sound of silence: the properties and functions of repressive Lys methyltransferases

Sound of silence: the properties and functions of repressive Lys methyltransferases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03051611v1

Sound of silence: the properties and functions of repressive Lys methyltransferases

About this item

Full title

Sound of silence: the properties and functions of repressive Lys methyltransferases

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2015-08, Vol.16 (8), p.499-513

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Lys methyltransferases (KMTs) belong to a large protein family that is characterized by the presence of the conserved catalytic SET domain. By using
S
-adenosyl-l-Met as a methyl group donor, KMTs are able to mono-, di- or trimethylate Lys residues on histones and on non-histone substrates.
KMTs have additional motifs that co...

Alternative Titles

Full title

Sound of silence: the properties and functions of repressive Lys methyltransferases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03051611v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03051611v1

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/nrm4029

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