Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition
Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition
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Washington, DC: American Society for the Advancement of Science
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English
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Washington, DC: American Society for the Advancement of Science
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Contents
Anandamide, an endogenous ligand for central cannabinoid receptors, is released from neurons on depolarization and rapidly inactivated. Anandamide inactivation is not completely understood, but it may occur by transport into cells or by enzymatic hydrolysis. The compound N-(4-hydroxyphenyl)arachidonylamide (AM404) was shown to inhibit high-affinity...
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Full title
Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition
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TN_cdi_hal_primary_oai_HAL_hal_03285460v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03285460v1
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.277.5329.1094