Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and pro...
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer
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Author / Creator
Roberti, Maria Paula , Yonekura, Satoru , Duong, Connie P. M. , Picard, Marion , Ferrere, Gladys , Tidjani Alou, Maryam , Rauber, Conrad , Iebba, Valerio , Lehmann, Christian H. K. , Amon, Lukas , Dudziak, Diana , Derosa, Lisa , Routy, Bertrand , Flament, Caroline , Richard, Corentin , Daillère, Romain , Fluckiger, Aurélie , Van Seuningen, Isabelle , Chamaillard, Mathias , Vincent, Audrey , Kourula, Stephanie , Opolon, Paule , Ly, Pierre , Pizzato, Eugénie , Becharef, Sonia , Paillet, Juliette , Klein, Christophe , Marliot, Florence , Pietrantonio, Filippo , Benoist, Stéphane , Scoazec, Jean-Yves , Dartigues, Peggy , Hollebecque, Antoine , Malka, David , Pagès, Franck , Galon, Jérôme , Gomperts Boneca, Ivo , Lepage, Patricia , Ryffel, Bernard , Raoult, Didier , Eggermont, Alexander , Vanden Berghe, Tom , Ghiringhelli, François , Vandenabeele, Peter , Kroemer, Guido and Zitvogel, Laurence
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The prognosis of colon cancer (CC) is dictated by tumor-infiltrating lymphocytes, including follicular helper T (T
FH
) cells and the efficacy of chemotherapy-induced immune responses. It remains unclear whether gut microbes contribute to the elicitation of T
FH
cell-driven responses. Here, we show that the ileal microbiota dictates tol...
Alternative Titles
Full title
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer
Authors, Artists and Contributors
Author / Creator
Yonekura, Satoru
Duong, Connie P. M.
Picard, Marion
Ferrere, Gladys
Tidjani Alou, Maryam
Rauber, Conrad
Iebba, Valerio
Lehmann, Christian H. K.
Amon, Lukas
Dudziak, Diana
Derosa, Lisa
Routy, Bertrand
Flament, Caroline
Richard, Corentin
Daillère, Romain
Fluckiger, Aurélie
Van Seuningen, Isabelle
Chamaillard, Mathias
Vincent, Audrey
Kourula, Stephanie
Opolon, Paule
Ly, Pierre
Pizzato, Eugénie
Becharef, Sonia
Paillet, Juliette
Klein, Christophe
Marliot, Florence
Pietrantonio, Filippo
Benoist, Stéphane
Scoazec, Jean-Yves
Dartigues, Peggy
Hollebecque, Antoine
Malka, David
Pagès, Franck
Galon, Jérôme
Gomperts Boneca, Ivo
Lepage, Patricia
Ryffel, Bernard
Raoult, Didier
Eggermont, Alexander
Vanden Berghe, Tom
Ghiringhelli, François
Vandenabeele, Peter
Kroemer, Guido
Zitvogel, Laurence
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03313676v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03313676v1
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X,1744-7933
DOI
10.1038/s41591-020-0882-8
