Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a rando...
Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial
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Author / Creator
Diéras, Véronique, MD , Han, Hyo S, MD , Kaufman, Bella, MD , Wildiers, Hans, Prof , Friedlander, Michael, Prof , Ayoub, Jean-Pierre, MD , Puhalla, Shannon L, MD , Bondarenko, Igor, Prof , Campone, Mario, Prof , Jakobsen, Erik H, MD , Jalving, Mathilde, MD , Oprean, Cristina, MD , Palácová, Marketa, MD , Park, Yeon Hee, MD , Shparyk, Yaroslav, MD , Yañez, Eduardo, MD , Khandelwal, Nikhil, PhD , Kundu, Madan G, PhD , Dudley, Matthew, PhD , Ratajczak, Christine K, PhD , Maag, David, PhD and Arun, Banu K, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundBRCA1 or BRCA2-mutated breast cancers are sensitive to poly(ADP-ribose) polymerase (PARP) inhibitors and platinum agents owing to deficiency in homologous recombination repair of DNA damage. In this trial, we compared veliparib versus placebo in combination with carboplatin and paclitaxel, and continued as monotherapy if carboplati...
Alternative Titles
Full title
Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Han, Hyo S, MD
Kaufman, Bella, MD
Wildiers, Hans, Prof
Friedlander, Michael, Prof
Ayoub, Jean-Pierre, MD
Puhalla, Shannon L, MD
Bondarenko, Igor, Prof
Campone, Mario, Prof
Jakobsen, Erik H, MD
Jalving, Mathilde, MD
Oprean, Cristina, MD
Palácová, Marketa, MD
Park, Yeon Hee, MD
Shparyk, Yaroslav, MD
Yañez, Eduardo, MD
Khandelwal, Nikhil, PhD
Kundu, Madan G, PhD
Dudley, Matthew, PhD
Ratajczak, Christine K, PhD
Maag, David, PhD
Arun, Banu K, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03492139v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03492139v1
Other Identifiers
ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(20)30447-2
