Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at on...
Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
In cancer cells, enhancer hijacking mediated by chromosomal alterations and/or increased deposition of acetylated histone H3 lysine 27 (H3K27ac) can support oncogene expression. However, how the chromatin conformation of enhancer–promoter interactions is affected by these events is unclear. In the present study, by comparing chromatin structure and...
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Full title
Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci
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TN_cdi_hal_primary_oai_HAL_hal_03565951v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03565951v1
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00842-x
