Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
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Author / Creator
Jacquelot, Nicolas , Seillet, Cyril , Wang, Minyu , Pizzolla, Angela , Liao, Yang , Hediyeh-zadeh, Soroor , Grisaru-Tal, Sharon , Louis, Cynthia , Huang, Qiutong , Schreuder, Jaring , Souza-Fonseca-Guimaraes, Fernando , de Graaf, Carolyn A. , Thia, Kevin , Macdonald, Sean , Camilleri, Mary , Luong, Kylie , Zhang, Shengbo , Chopin, Michael , Molden-Hauer, Tristan , Nutt, Stephen L. , Umansky, Viktor , Ciric, Bogoljub , Groom, Joanna R. , Foster, Paul S. , Hansbro, Philip M. , McKenzie, Andrew N. J. , Gray, Daniel H. D. , Behren, Andreas , Cebon, Jonathan , Vivier, Eric , Wicks, Ian P. , Trapani, Joseph A. , Munitz, Ariel , Davis, Melissa J. , Shi, Wei , Neeson, Paul J. and Belz, Gabrielle T.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Group 2 innate lymphoid cells (ILC2s) are essential to maintain tissue homeostasis. In cancer, ILC2s can harbor both pro-tumorigenic and anti-tumorigenic functions, but we know little about their underlying mechanisms or whether they could be clinically relevant or targeted to improve patient outcomes. Here, we found that high ILC2 infiltration in...
Alternative Titles
Full title
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
Authors, Artists and Contributors
Author / Creator
Seillet, Cyril
Wang, Minyu
Pizzolla, Angela
Liao, Yang
Hediyeh-zadeh, Soroor
Grisaru-Tal, Sharon
Louis, Cynthia
Huang, Qiutong
Schreuder, Jaring
Souza-Fonseca-Guimaraes, Fernando
de Graaf, Carolyn A.
Thia, Kevin
Macdonald, Sean
Camilleri, Mary
Luong, Kylie
Zhang, Shengbo
Chopin, Michael
Molden-Hauer, Tristan
Nutt, Stephen L.
Umansky, Viktor
Ciric, Bogoljub
Groom, Joanna R.
Foster, Paul S.
Hansbro, Philip M.
McKenzie, Andrew N. J.
Gray, Daniel H. D.
Behren, Andreas
Cebon, Jonathan
Vivier, Eric
Wicks, Ian P.
Trapani, Joseph A.
Munitz, Ariel
Davis, Melissa J.
Shi, Wei
Neeson, Paul J.
Belz, Gabrielle T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03566011v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03566011v1
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-00943-z
