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Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression

Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03606419v1

Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression

Publication information

Publisher

American Society for Clinical Investigation

More information

Scope and Contents

Contents

It has recently been demonstrated that memory B cells can reenter and reengage germinal center (GC) reactions, opening the possibility that multi-hit lymphomagenesis gradually occurs throughout life during successive immunological challenges. Here, we investigated this scenario in follicular lymphoma (FL), an indolent GC-derived malignancy. We deve...

Alternative Titles

Full title

Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03606419v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03606419v1

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI72415

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