SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease
SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease
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Author / Creator
CNR-MAJ collaborators , The CNR-MAJ collaborators , Nicolas, G , Charbonnier, C , Wallon, D , Quenez, O , Bellenguez, C , Grenier-Boley, B , Rousseau, S , Richard, A-C , Rovelet-Lecrux, A , Le Guennec, K , Bacq, D , Garnier, J-G , Olaso, R , Boland, A , Meyer, V , Deleuze, J-F , Amouyel, P , Munter, H M , Bourque, G , Lathrop, M , Frebourg, T , Redon, R , Letenneur, L , Dartigues, J-F , Génin, E , Lambert, J-C , Hannequin, D and Campion, D
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The SORL1 protein plays a protective role against the secretion of the amyloid β peptide, a key event in the pathogeny of Alzheimer’s disease. We assessed the impact of
SORL1
rare variants in early-onset Alzheimer’s disease (EOAD) in a case–control setting. We conducted a whole exome analysis among 484 French EOAD patients and 498 ethnically...
Alternative Titles
Full title
SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
The CNR-MAJ collaborators
Nicolas, G
Charbonnier, C
Wallon, D
Quenez, O
Bellenguez, C
Grenier-Boley, B
Rousseau, S
Richard, A-C
Rovelet-Lecrux, A
Le Guennec, K
Bacq, D
Garnier, J-G
Olaso, R
Boland, A
Meyer, V
Deleuze, J-F
Amouyel, P
Munter, H M
Bourque, G
Lathrop, M
Frebourg, T
Redon, R
Letenneur, L
Dartigues, J-F
Génin, E
Lambert, J-C
Hannequin, D
Campion, D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03630222v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03630222v1
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/mp.2015.121
