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Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03699580v1

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

About this item

Full title

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2022-08, Vol.18 (8), p.894-903

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Membrane proteins, including ion channels, receptors and transporters, are often composed of multiple subunits and can form large complexes. Their specific composition in native tissues is difficult to determine and remains largely unknown. In this study, we developed a method for determining the subunit composition of endogenous cell surface prote...

Alternative Titles

Full title

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03699580v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03699580v1

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-022-01050-2

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