Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of my...
Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
DNA methylation, a major biological process regulating the transcription, contributes to the pathophysiology of hematologic malignancies, and hypomethylating agents are commonly used to treat myelodysplastic syndromes (MDS) and acute myeloid leukemias (AML). In these diseases, bone marrow mesenchymal stromal cells (MSCs) play a key supportive role...
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Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia
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TN_cdi_hal_primary_oai_HAL_hal_03713209v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03713209v1
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ISSN
0929-1903
E-ISSN
1476-5500,0929-1903
DOI
10.1038/s41417-022-00441-w
