Succinate: A Serum Biomarker of SDHB-Mutated Paragangliomas and Pheochromocytomas
Succinate: A Serum Biomarker of SDHB-Mutated Paragangliomas and Pheochromocytomas
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Publisher
US: Oxford University Press
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Language
English
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Publisher
US: Oxford University Press
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Abstract
Context
Pheochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumors that are frequently associated with succinate dehydrogenase (SDH) germline mutations. When mutated, SDH losses its function, thus leading to succinate accumulation.
Objective
In this study, we evaluated serum succinate levels as a new metabolic b...
Alternative Titles
Full title
Succinate: A Serum Biomarker of SDHB-Mutated Paragangliomas and Pheochromocytomas
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TN_cdi_hal_primary_oai_HAL_hal_03837365v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03837365v1
Other Identifiers
ISSN
0021-972X
E-ISSN
1945-7197
DOI
10.1210/clinem/dgac474
