BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chem...
BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells
About this item
Full title
Author / Creator
Azzoni, Violette , Wicinski, Julien , Macario, Manon , Castagné, Martin , Finetti, Pascal , Ambrosova, Katerina , Rouault, Célia , Sergé, Arnaud , Farina, Anne , Agavnian, Emilie , Coslet, Sergiu , Josselin, Emmanuelle , Guille, Arnaud , Adelaide, José , Zacharioudakis, Emmanouil , Castellano, Rémy , Bertucci, Francois , Birnbaum, Daniel , Rodriguez, Raphaël , Charafe-Jauffret, Emmanuelle and Ginestier, Christophe
Publisher
Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Abstract Replication stress (RS) has a pivotal role in tumor initiation, progression, or therapeutic resistance. In this study, we depicted the mechanism of breast cancer stem cells’ (bCSCs) response to RS and its clinical implication. We demonstrated that bCSCs present a limited level of RS compared with non-bCSCs in patient samples. We described...
Alternative Titles
Full title
BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells
Authors, Artists and Contributors
Author / Creator
Wicinski, Julien
Macario, Manon
Castagné, Martin
Finetti, Pascal
Ambrosova, Katerina
Rouault, Célia
Sergé, Arnaud
Farina, Anne
Agavnian, Emilie
Coslet, Sergiu
Josselin, Emmanuelle
Guille, Arnaud
Adelaide, José
Zacharioudakis, Emmanouil
Castellano, Rémy
Bertucci, Francois
Birnbaum, Daniel
Rodriguez, Raphaël
Charafe-Jauffret, Emmanuelle
Ginestier, Christophe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04053791v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04053791v1
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04538-w
