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Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin...

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04089083v1

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

About this item

Full title

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Author / Creator

KEYNOTE-966 Investigators , Ueno, Makoto , Finn, Richard S , Ren, Zhenggang , Yau, Thomas , Klümpen, Heinz-Josef , Chan, Stephen L , Park, Joon Oh , Pelzer, Uwe , Yu, Li , Siegel, Abby B , Edeline, Julien , Akce, Mehmet , Asselah, Jamil , Assenat, Eric , Aubin, Francine , Barajas, Olga , Ben-Aharon, Irit , Beri, Nina , Berres, Marie-Luise , Brandi, Giovanni , Butthongkomvong, Kritiya , Camandaroba, Marcos , Carballido, Marcela , Chan, Stephan Lam , Chen, Jen-Shi , Chen, Xiaoming , Chon, Hong Jae , Cubillo Gracian, Antonio , Davis, Sarah , De Vos, Judith , Falcone, Alfredo , Fernandez, Plinio , Finn, Richard , Franke, Fabio , Furukawa, Masayuki , Furuse, Junji , Geboes, Karen , Geng, Zhimin , Geva, Ravit , Gou, Hongfeng , Grasselli, Julieta , Hao, Chunyi , Hatoum, Hassan , Heinemann, Volker , Jeyasingam, Vaishnavi , Jimenez Fonseca, Paula , Kasper-Virchow, Stefan , Kelley, Robin , Kim, Jong Gwang , Kinupe Abrahao, Ana Beatriz , Kochenderfer, Mark , Lee, Choong-kun , Lee, Hyun Woo , Lee, Myung Ah , Lee, Wai Man Sarah , Li, Dongliang , Liang, Houjie , Lim, Chun Sen , Low, John , Mao, Yimin , Masi, Gianluca , McCune, Steven , McWhirter, Elaine , Mendez, Guillermo , Mizutani, Tomonori , Moniz, Camila , Morales, Luisa , Munoz Martin, Andres Jesús , Oh, Sang Cheul , Painemal, Claudio , Peng, Chuang , Pezet, Denis , Roohullah, Aflah , Ryu, Hyewon , Schulze, Kornelius , Scott-Brown, Martin , Seufferlein, Thomas , Smolenschi, Cristina , Sookprasert, Aumkhae , Soparattanapaisarn, Nopadol , Starling, Naureen , Stein, Stacey , Sugimoto, Rie , Suksombooncharoen, Thatthan , Tam, Vincent , Tan, Ai Lian , Tanasanvimon, Suebpong , Tonini, Giuseppe , Tsuji, Akihito , Verslype, Chris , Victorino, Ana Paula , Wade, James , Waldschmidt, Dirk Thomas , Wang, Lu , Wan Isahk, Wan Zamaniah , Weschenfelder, Rui , Wong, Chun Yin , Yang, Xuezhong , Yau, Thomas and Zhao, Haitao

Publisher

England: Elsevier Ltd

Journal title

The Lancet (British edition), 2023-06, Vol.401 (10391), p.1853-1865

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Biliary tract cancers, which arise from the intrahepatic or extrahepatic bile ducts and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide. The standard-of-care treatment for advanced biliary tract cancer is chemotherapy with gemcitabine and cisplatin. Because most biliary tract cancers have an immune-suppressed...

Alternative Titles

Full title

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Authors, Artists and Contributors

Author / Creator

KEYNOTE-966 Investigators
Ueno, Makoto
Finn, Richard S
Ren, Zhenggang
Yau, Thomas
Klümpen, Heinz-Josef
Chan, Stephen L
Park, Joon Oh
Pelzer, Uwe
Yu, Li
Siegel, Abby B
Edeline, Julien
Akce, Mehmet
Asselah, Jamil
Assenat, Eric
Aubin, Francine
Barajas, Olga
Ben-Aharon, Irit
Beri, Nina
Berres, Marie-Luise
Brandi, Giovanni
Butthongkomvong, Kritiya
Camandaroba, Marcos
Carballido, Marcela
Chan, Stephan Lam
Chen, Jen-Shi
Chen, Xiaoming
Chon, Hong Jae
Cubillo Gracian, Antonio
Davis, Sarah
De Vos, Judith
Falcone, Alfredo
Fernandez, Plinio
Finn, Richard
Franke, Fabio
Furukawa, Masayuki
Furuse, Junji
Geboes, Karen
Geng, Zhimin
Geva, Ravit
Gou, Hongfeng
Grasselli, Julieta
Hao, Chunyi
Hatoum, Hassan
Heinemann, Volker
Jeyasingam, Vaishnavi
Jimenez Fonseca, Paula
Kasper-Virchow, Stefan
Kelley, Robin
Kim, Jong Gwang
Kinupe Abrahao, Ana Beatriz
Kochenderfer, Mark
Lee, Choong-kun
Lee, Hyun Woo
Lee, Myung Ah
Lee, Wai Man Sarah
Li, Dongliang
Liang, Houjie
Lim, Chun Sen
Low, John
Mao, Yimin
Masi, Gianluca
McCune, Steven
McWhirter, Elaine
Mendez, Guillermo
Mizutani, Tomonori
Moniz, Camila
Morales, Luisa
Munoz Martin, Andres Jesús
Oh, Sang Cheul
Painemal, Claudio
Peng, Chuang
Pezet, Denis
Roohullah, Aflah
Ryu, Hyewon
Schulze, Kornelius
Scott-Brown, Martin
Seufferlein, Thomas
Smolenschi, Cristina
Sookprasert, Aumkhae
Soparattanapaisarn, Nopadol
Starling, Naureen
Stein, Stacey
Sugimoto, Rie
Suksombooncharoen, Thatthan
Tam, Vincent
Tan, Ai Lian
Tanasanvimon, Suebpong
Tonini, Giuseppe
Tsuji, Akihito
Verslype, Chris
Victorino, Ana Paula
Wade, James
Waldschmidt, Dirk Thomas
Wang, Lu
Wan Isahk, Wan Zamaniah
Weschenfelder, Rui
Wong, Chun Yin
Yang, Xuezhong
Yau, Thomas
Zhao, Haitao

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04089083v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04089083v1

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(23)00727-4

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