Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protect...
Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Histone acetylation is important in regulating DNA accessibility. Multifunctional Sin3 proteins bind histone deacetylases (HDACs) to assemble silencing complexes that selectively target chromatin. We show that, in fission yeast, an essential HDAC, Clr6, exists in two distinct Sin3 core complexes. Complex I contains an essential Sin3 homolog, Pst1,...
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Full title
Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection
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TN_cdi_hal_primary_oai_HAL_hal_04298008v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04298008v1
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb1239
