Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocy...
Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Background
In obesity, adipose tissue dysfunction resulting from excessive fat accumulation leads to systemic insulin resistance (IR), the underlying alteration of Type 2 Diabetes. The specific pathways dysregulated in dysfunctional adipocytes and the extent to which it affects adipose metabolic functions remain incompletely characterized.
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Full title
Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes
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TN_cdi_hal_primary_oai_HAL_hal_04311672v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04311672v1
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ISSN
0307-0565
E-ISSN
1476-5497,0307-0565
DOI
10.1038/s41366-021-01021-y