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Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04312352v1

Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

About this item

Full title

Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

Publisher

Washington, DC: Endocrine Society

Journal title

The journal of clinical endocrinology and metabolism, 2018-05, Vol.103 (5), p.1929-1939

Language

English

Formats

Publication information

Publisher

Washington, DC: Endocrine Society

More information

Scope and Contents

Contents

Abstract
Purpose
The molecular pathogenesis of growth hormone-secreting pituitary adenomas is not fully understood. Cytogenetic alterations might serve as alternative driver events in GNAS mutation–negative somatotroph tumors.
Experimental Design
We performed cytogenetic profiling of pituitary adenomas obtained from 39 patients with acr...

Alternative Titles

Full title

Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04312352v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04312352v1

Other Identifiers

ISSN

0021-972X

E-ISSN

1945-7197

DOI

10.1210/jc.2017-02287

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