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Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04496734v1

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

About this item

Full title

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Publisher

Wiley Open Access

Journal title

EMBO molecular medicine, 2015-06, Vol.7 (6), p.802-818

Language

English

Formats

Publication information

Publisher

Wiley Open Access

More information

Scope and Contents

Contents

The metabolic syndrome covers metabolic abnormalities including obesity and type 2 diabetes (T2D). T2D is characterized by insulin resistance resulting from both environmental and genetic factors. A genome-wide association study (GWAS) published in 2010 identified TP53INP1 as a new T2D susceptibility locus, but a pathological mechanism was not iden...

Alternative Titles

Full title

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04496734v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04496734v1

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201404318

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