Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis
Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis
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Author / Creator
International ICI-Myocarditis Registry , Fenioux, Charlotte , Abbar, Baptiste , Boussouar, Samia , Bretagne, Marie , Power, John R. , Moslehi, Javid J. , Gougis, Paul , Amelin, Damien , Dechartres, Agnès , Lehmann, Lorenz H. , Courand, Pierre-Yves , Cautela, Jennifer , Alexandre, Joachim , Procureur, Adrien , Rozes, Antoine , Leonard-Louis, Sarah , Qin, Juan , Cheynier, Rémi , Charmeteau-De Muylder, Benedicte , Redheuil, Alban , Tubach, Florence , Cadranel, Jacques , Milon, Audrey , Ederhy, Stéphane , Similowski, Thomas , Johnson, Douglas B. , Pizzo, Ian , Catalan, Toniemarie , Benveniste, Olivier , Hayek, Salim S. , Allenbach, Yves , Rosenzwajg, Michelle , Dolladille, Charles and Salem, Joe-Elie
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Immune checkpoint inhibitors (ICI) have transformed the therapeutic landscape in oncology. However, ICI can induce uncommon life-threatening autoimmune T-cell-mediated myotoxicities, including myocarditis and myositis. The thymus plays a critical role in T cell maturation. Here we demonstrate that thymic alterations are associated with increased in...
Alternative Titles
Full title
Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis
Authors, Artists and Contributors
Author / Creator
Fenioux, Charlotte
Abbar, Baptiste
Boussouar, Samia
Bretagne, Marie
Power, John R.
Moslehi, Javid J.
Gougis, Paul
Amelin, Damien
Dechartres, Agnès
Lehmann, Lorenz H.
Courand, Pierre-Yves
Cautela, Jennifer
Alexandre, Joachim
Procureur, Adrien
Rozes, Antoine
Leonard-Louis, Sarah
Qin, Juan
Cheynier, Rémi
Charmeteau-De Muylder, Benedicte
Redheuil, Alban
Tubach, Florence
Cadranel, Jacques
Milon, Audrey
Ederhy, Stéphane
Similowski, Thomas
Johnson, Douglas B.
Pizzo, Ian
Catalan, Toniemarie
Benveniste, Olivier
Hayek, Salim S.
Allenbach, Yves
Rosenzwajg, Michelle
Dolladille, Charles
Salem, Joe-Elie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04510220v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04510220v1
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X,1744-7933
DOI
10.1038/s41591-023-02591-2