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Synthesis of bicyclo[4.2.0]octane ring of kingianin via [2+2] ketene cycloaddition

Synthesis of bicyclo[4.2.0]octane ring of kingianin via [2+2] ketene cycloaddition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04549821v1

Synthesis of bicyclo[4.2.0]octane ring of kingianin via [2+2] ketene cycloaddition

About this item

Full title

Synthesis of bicyclo[4.2.0]octane ring of kingianin via [2+2] ketene cycloaddition

Publisher

Gebze: ACG Publications

Journal title

Organic communications, 2024-01, Vol.17 (1), p.56-62

Language

English

Formats

Publication information

Publisher

Gebze: ACG Publications

More information

Scope and Contents

Contents

Kingianins are pentacyclic polyketides isolated from Endiandra kingiana. They exhibit promising activity in inhibiting anti-apoptotic proteins (i.e Bcl-xL and Mcl-1) and anti-diabetic proteins (α-glucosidase) at micromolar levels. Due to their structural complexity and intriguing biological activity, researchers are increasingly focussing on design...

Alternative Titles

Full title

Synthesis of bicyclo[4.2.0]octane ring of kingianin via [2+2] ketene cycloaddition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04549821v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04549821v1

Other Identifiers

ISSN

1307-6175

E-ISSN

1307-6175

DOI

10.25135/acg.oc.164.2402.3124

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