Human embryonic stem cells reveal recurrent genomic instability at 20q11.21
Human embryonic stem cells reveal recurrent genomic instability at 20q11.21
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
During long-term culture, human embryonic stem (hES) cells may acquire chromosomal abnormalities that compromise their potential clinical utility. Lefort
et al
. show that an amplification at 20q11.21 arose at relatively late passage number in three of five hES cell lines.
By analyzing five human embryonic stem (hES) cell lines over long-t...
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Full title
Human embryonic stem cells reveal recurrent genomic instability at 20q11.21
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TN_cdi_hal_primary_oai_HAL_hal_04963815v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04963815v1
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1509
