Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1
Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1
About this item
Full title
Author / Creator
Dauvilliers, Yves , Mignot, Emmanuel , del Río Villegas, Rafael , Du, Yeting , Hanson, Elizabeth , Inoue, Yuichi , Kadali, Harisha , Koundourakis, Elena , Meyer, Seetha , Rogers, Raquel , Scammell, Thomas E. , Sheikh, Sarah I. , Swick, Todd , Szakács, Zoltan , von Rosenstiel, Philipp , Wu, Jingtao , Zeitz, Heidi , Murthy, N. Venkatesha , Plazzi, Giuseppe and von Hehn, Christian
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Narcolepsy type 1 is caused by severe loss or lack of brain orexin neuropeptides.
We conducted a phase 2, randomized, placebo-controlled trial of TAK-994, an oral orexin receptor 2-selective agonist, in patients with narcolepsy type 1. Patients with confirmed narcolepsy type 1 according to clinical criteria were randomly assigned to receive twic...
Alternative Titles
Full title
Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1
Authors, Artists and Contributors
Author / Creator
Mignot, Emmanuel
del Río Villegas, Rafael
Du, Yeting
Hanson, Elizabeth
Inoue, Yuichi
Kadali, Harisha
Koundourakis, Elena
Meyer, Seetha
Rogers, Raquel
Scammell, Thomas E.
Sheikh, Sarah I.
Swick, Todd
Szakács, Zoltan
von Rosenstiel, Philipp
Wu, Jingtao
Zeitz, Heidi
Murthy, N. Venkatesha
Plazzi, Giuseppe
von Hehn, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04965885v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04965885v1
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2301940
