Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcript...
Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock
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Col, Edwige , Hoghoughi, Neda , Dufour, Solenne , Penin, Jessica , Koskas, Sivan , Faure, Virginie , Ouzounova, Maria , Hernandez-Vargash, Hector , Reynoird, Nicolas , Daujat, Sylvain , Folco, Eric , Vigneron, Marc , Schneider, Robert , Verdel, André , Khochbin, Saadi , Herceg, Zdenko , Caron, Cécile and Vourc’h, Claire
Publisher
Nature Publishing Group
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English
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Nature Publishing Group
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Abstract The heat shock response is characterized by the transcriptional activation of both hsp genes and noncoding and repeated satellite III DNA sequences located at pericentric heterochromatin. Both events are under the control of Heat Shock Factor I (HSF1). Here we show that under heat shock, HSF1 recruits major cellular acetyltransferases, GCN...
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Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock
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TN_cdi_hal_primary_oai_HAL_hal_04980603v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04980603v1
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05343-8
