Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation:...
Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial
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Author / Creator
de Langen, Adrianus Johannes , Johnson, Melissa L , Mazieres, Julien , Dingemans, Anne-Marie C , Mountzios, Giannis , Pless, Miklos , Wolf, Jürgen , Schuler, Martin , Lena, Hervé , Skoulidis, Ferdinandos , Yoneshima, Yasuto , Kim, Sang-We , Linardou, Helena , Novello, Silvia , van der Wekken, Anthonie J , Chen, Yuanbin , Peters, Solange , Felip, Enriqueta , Solomon, Benjamin J , Ramalingam, Suresh S. , Dooms, Christophe , Lindsay, Colin R , Ferreira, Carlos Gil , Blais, Normand , Obiozor, Cynthia C , Wang, Yang , Mehta, Bhakti , Varrieur, Tracy , Ngarmchamnanrith, Gataree , Stollenwerk, Björn , Waterhouse, David , Paz-Ares, Luis and CodeBreaK 200 Investigators
Publisher
Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Sotorasib is a specific, irreversible inhibitor of the GTPase protein, KRASG12C. We compared the efficacy and safety of sotorasib with a standard-of-care treatment in patients with non-small-cell lung cancer (NSCLC) with the KRASG12C mutation who had been previously treated with other anticancer drugs.
We conducted a randomised, open-label phase...
Alternative Titles
Full title
Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Johnson, Melissa L
Mazieres, Julien
Dingemans, Anne-Marie C
Mountzios, Giannis
Pless, Miklos
Wolf, Jürgen
Schuler, Martin
Lena, Hervé
Skoulidis, Ferdinandos
Yoneshima, Yasuto
Kim, Sang-We
Linardou, Helena
Novello, Silvia
van der Wekken, Anthonie J
Chen, Yuanbin
Peters, Solange
Felip, Enriqueta
Solomon, Benjamin J
Ramalingam, Suresh S.
Dooms, Christophe
Lindsay, Colin R
Ferreira, Carlos Gil
Blais, Normand
Obiozor, Cynthia C
Wang, Yang
Mehta, Bhakti
Varrieur, Tracy
Ngarmchamnanrith, Gataree
Stollenwerk, Björn
Waterhouse, David
Paz-Ares, Luis
CodeBreaK 200 Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04989148v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04989148v1
Other Identifiers
ISSN
0140-6736,1474-547X
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(23)00221-0