VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation
VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation
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Author / Creator
Grieder, Taryn E , Herman, Melissa A , Contet, Candice , Tan, Laura A , Vargas-Perez, Hector , Cohen, Ami , Chwalek, Michal , Maal-Bared, Geith , Freiling, John , Schlosburg, Joel E , Clarke, Laura , Crawford, Elena , Koebel, Pascale , Repunte-Canonigo, Vez , P Sanna, Pietro , Tapper, Andrew R , Roberto, Marisa , Kieffer, Brigitte L , Sawchenko, Paul E , Koob, George F , van der Kooy, Derek and George, Olivier
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Corticotropin-releasing factor (CRF) and dopamine (DA) are critical for stress and motivation, respectively. The authors show that CRF is synthesized in DA neurons and released in the ventral tegmental area, where it affects GABAergic inputs to DA neurons and mediates the motivational effects of nicotine withdrawal and escalation of nicotine intake...
Alternative Titles
Full title
VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation
Authors, Artists and Contributors
Author / Creator
Herman, Melissa A
Contet, Candice
Tan, Laura A
Vargas-Perez, Hector
Cohen, Ami
Chwalek, Michal
Maal-Bared, Geith
Freiling, John
Schlosburg, Joel E
Clarke, Laura
Crawford, Elena
Koebel, Pascale
Repunte-Canonigo, Vez
P Sanna, Pietro
Tapper, Andrew R
Roberto, Marisa
Kieffer, Brigitte L
Sawchenko, Paul E
Koob, George F
van der Kooy, Derek
George, Olivier
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04996619v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04996619v1
Other Identifiers
ISSN
1097-6256,1546-1726
E-ISSN
1546-1726
DOI
10.1038/nn.3872
