Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly
Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
New data show that depletion of histone chaperone CAF-1 in mouse embryonic stem (ES) cells induces early embryonic-like cells that exhibit gene-expression patterns and reprogramming efficiencies characteristic of 2-cell-stage populations that arise spontaneously in ES-cell culture, thus suggesting that altered chromatin assembly contributes to diff...
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Full title
Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly
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TN_cdi_hal_primary_oai_HAL_hal_05004290v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_05004290v1
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3066
