Polycystin deficiency induces dopamine-reversible alterations in flow-mediated dilatation and vascul...
Polycystin deficiency induces dopamine-reversible alterations in flow-mediated dilatation and vascular nitric oxide release in humans
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Author / Creator
Lorthioir, Aurélien , Joannidès, Robinson , Rémy-Jouet, Isabelle , Fréguin-Bouilland, Caroline , Iacob, Michèle , Roche, Clothilde , Monteil, Christelle , Lucas, Danièle , Renet, Sylvanie , Audrézet, Marie-Pierre , Godin, Michel , Richard, Vincent , Thuillez, Christian , Guerrot, Dominique and Bellien, Jérémy
Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Autosomal dominant polycystic kidney disease (ADPKD) is a renal hereditary disorder associated with increased cardiovascular mortality, due to mutations in polycystin-1 and polycystin-2 genes. Endothelial polycystin-deficient cells have an altered mechanosensitivity to fluid shear stress and subsequent deficit in calcium-induced nitric oxide releas...
Alternative Titles
Full title
Polycystin deficiency induces dopamine-reversible alterations in flow-mediated dilatation and vascular nitric oxide release in humans
Authors, Artists and Contributors
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Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_02296634v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02296634v1
Other Identifiers
ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2014.241
