Chimeric oncogene regulates the EGR2 sarcoma susceptibility gene via a GGAA-microsatellite
Chimeric oncogene regulates the EGR2 sarcoma susceptibility gene via a GGAA-microsatellite
About this item
Full title
Author / Creator
Grünewald, Thomas G P , Bernard, Virginie , Gilardi-Hebenstreit, Pascale , Raynal, Virginie , Surdez, Didier , Aynaud, Marie-Ming , Cidre-Aranaz, Florencia , Mirabeau, Olivier , Tirode, Franck , Pérot, Gaëlle , Jonker, Anneliene , Lucchesi, Carlo , Le Deley, Marie-Cécile , Oberlin, Odile , Marec-Bérard, Perrine , Véron, Amélie , Reynaud, Stéphanie , Lapouble, Eve , Boeva, Valentina , Rio Frio, Thomas , Alonso, Javier , Pierron, Gaëlle , Cancel-Tassin, Geraldine , Cussenot, Olivier , Cox, David , Chanock, Stephen , Charnay, Patrick and Delattre, Olivier
Publisher
Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Deciphering the ways in which somatic mutations and germline susceptibility variants cooperate to promote cancer is challenging. Ewing sarcoma is characterized by fusions between EWSR1 and members of the ETS gene family, usually EWSR1-FLI1, leading to the generation of oncogenic transcription factors that bind DNA at GGAA motifs. A recent genome-wi...
Alternative Titles
Full title
Chimeric oncogene regulates the EGR2 sarcoma susceptibility gene via a GGAA-microsatellite
Authors, Artists and Contributors
Author / Creator
Bernard, Virginie
Gilardi-Hebenstreit, Pascale
Raynal, Virginie
Surdez, Didier
Aynaud, Marie-Ming
Cidre-Aranaz, Florencia
Mirabeau, Olivier
Tirode, Franck
Pérot, Gaëlle
Jonker, Anneliene
Lucchesi, Carlo
Le Deley, Marie-Cécile
Oberlin, Odile
Marec-Bérard, Perrine
Véron, Amélie
Reynaud, Stéphanie
Lapouble, Eve
Boeva, Valentina
Rio Frio, Thomas
Alonso, Javier
Pierron, Gaëlle
Cancel-Tassin, Geraldine
Cussenot, Olivier
Cox, David
Chanock, Stephen
Charnay, Patrick
Delattre, Olivier
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_02440399v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02440399v1
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3363
