Decoding and unlocking the BCL-2 dependency of cancer cells
Decoding and unlocking the BCL-2 dependency of cancer cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
The balance between pro- and anti-apoptotic activities of BCL-2 family members is tipped towards survival in many cancer cells, thus allowing them to survive various stressful environments, tumour stress phenotypes and/or oncogene-induced death signals.
As death signals may persist during tumour progression, cancer cells may be add...
Alternative Titles
Full title
Decoding and unlocking the BCL-2 dependency of cancer cells
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TN_cdi_hal_primary_oai_HAL_inserm_02481124v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02481124v1
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3538
