Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophi...
Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina
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Author / Creator
Ameline, B , Tshilenge, K-T , Weber, M , Biget, M , Libeau, L , Caplette, R , Mendes-Madeira, A , Provost, N , Guihal, C , Picaud, S , Moullier, P , Pichard, V , Cronin, T and Isiegas, C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Several preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of long-term expression of these optogenes on the diseased retina in a large animal model of retinal degeneration, the RPE65-def...
Alternative Titles
Full title
Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_02894245v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02894245v1
Other Identifiers
ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/gt.2017.63
