Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?
Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?
About this item
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Author / Creator
Publisher
MDPI
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Language
English
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Publisher
MDPI
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Scope and Contents
Contents
Liver X Receptors (LXR) alpha and beta are two members of nuclear receptor superfamily documented as endogenous cholesterol sensors. Following conversion of cholesterol in oxysterol, both LXR isoforms detect intracellular concentrations and act as transcription factors to promote expression of target genes. Among their numerous physiological roles,...
Alternative Titles
Full title
Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?
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Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_03171292v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_03171292v1
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ISSN
1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms20163858
