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Inhibiting Endothelin Receptors withMacitentan Strengthens the Bone Protective Action of RANKL Inhib...

Inhibiting Endothelin Receptors withMacitentan Strengthens the Bone Protective Action of RANKL Inhib...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_03625367v1

Inhibiting Endothelin Receptors withMacitentan Strengthens the Bone Protective Action of RANKL Inhibition and Reduces Metastatic Dissemination in Osteosarcoma

About this item

Full title

Inhibiting Endothelin Receptors withMacitentan Strengthens the Bone Protective Action of RANKL Inhibition and Reduces Metastatic Dissemination in Osteosarcoma

Publisher

MDPI

Journal title

Cancers, 2022-03, Vol.14 (7)

Language

English

Formats

Publication information

Publisher

MDPI

More information

Scope and Contents

Contents

Current treatments for osteosarcoma, combining conventional polychemotherapy and surgery, make it possible to attain a five-year survival rate of 70% in affected individuals. The presence of chemoresistance and metastases significantly shorten the patient’s lifespan, making identification of new therapeutic tools essential. Inhibiting bone resorpti...

Alternative Titles

Full title

Inhibiting Endothelin Receptors withMacitentan Strengthens the Bone Protective Action of RANKL Inhibition and Reduces Metastatic Dissemination in Osteosarcoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_inserm_03625367v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_03625367v1

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers14071765

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