Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection
Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection
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Nature Publishing Group
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English
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Nature Publishing Group
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Abstract Host protection against cutaneous herpes simplex virus 1 (HSV-1) infection relies on the induction of a robust adaptive immune response. Here, we show that Nav 1.8 + sensory neurons, which are involved in pain perception, control the magnitude of CD8 T cell priming and expansion in HSV-1-infected mice. The ablation of Nav 1.8 -expressing s...
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Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection
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TN_cdi_hal_primary_oai_HAL_inserm_04871414v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_04871414v1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22841-6
