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Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in...

Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_mnhn_03930307v1

Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models

About this item

Full title

Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European radiology, 2017-10, Vol.27 (10), p.4435-4444

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Objective
This study aimed to explore the antitumour effect of the DNA repair inhibitor, DT01 (the cholesterol conjugated form of Dbait), as an adjunct treatment to enhance the therapeutic efficacy of transarterial chemoembolization (TACE) in pre-clinical models of hepatocellular carcinoma (HCC).
Methods
A rabbit model bearing liver tumour...

Alternative Titles

Full title

Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_mnhn_03930307v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_mnhn_03930307v1

Other Identifiers

ISSN

0938-7994

E-ISSN

1432-1084

DOI

10.1007/s00330-017-4792-1

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