An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The CRISPR system in bacteria and archaea provides adaptive immunity against mobile genetic elements. Type III CRISPR systems detect viral RNA, resulting in the activation of two regions of the Cas10 protein: an HD nuclease domain (which degrades viral DNA)
1
,
2
and a cyclase domain (which synthesizes cyclic oligoadenylates from ATP)
Alternative Titles
Full title
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_pasteur_02559915v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_pasteur_02559915v1
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1909-5
