T1 Rev-erbα, a novel anti-inflammatory target, modifies the circadian oscillation of pulmonary infla...
T1 Rev-erbα, a novel anti-inflammatory target, modifies the circadian oscillation of pulmonary inflammation
About this item
Full title
Publisher
BMJ Publishing Group Ltd and British Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
BMJ Publishing Group Ltd and British Thoracic Society
More information
Scope and Contents
Contents
IntroductionMost inflammatory diseases demonstrate diurnal variation in severity, for example, chronic obstructive pulmonary disease (COPD) and asthma. We now show that the macrophage inflammatory response is regulated by the circadian cellular clock through Rev-erbα, a nuclear receptor. Additionally, a Rev-erbα ligand (GSK414112) regulates a disti...
Alternative Titles
Full title
T1 Rev-erbα, a novel anti-inflammatory target, modifies the circadian oscillation of pulmonary inflammation
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_istex_primary_ark_67375_NVC_8G0C2SBG_Q
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_istex_primary_ark_67375_NVC_8G0C2SBG_Q
Other Identifiers
ISSN
0040-6376
E-ISSN
1468-3296
DOI
10.1136/thx.2010.150896.1
