Regeneration of β -adrenergic Receptors in Senescent Rats: A Study Using an Irreversible Binding Ant...
Regeneration of β -adrenergic Receptors in Senescent Rats: A Study Using an Irreversible Binding Antagonist
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
The drug used in this study, bromoacetylalprenololmenthane, has the ability to bind and block irreversibly β -adrenergic receptors. The drug was bound to membranes prepared from hearts, lungs, and brains of both senescent and young rats with a similar affinity. When this drug was injected into rats in nontoxic doses (up to 70 mg/kg), up to 90% of β...
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Full title
Regeneration of β -adrenergic Receptors in Senescent Rats: A Study Using an Irreversible Binding Antagonist
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TN_cdi_jstor_primary_12606
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_12606
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.79.14.4424