Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase cen...
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Differences between the structures of bacterial, archaeal, and eukaryotic ribosomes account for the selective action of antibiotics. Even minor variations in the structure of ribosomes of different bacterial species may lead to idiosyncratic, species-specific interactions of the drugs with their targets. Although crystallographic structures of anti...
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Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action
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TN_cdi_jstor_primary_20779932
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_20779932
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1007988107