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Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase cen...

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase cen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_20779932

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

About this item

Full title

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (40), p.17152-17157

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Differences between the structures of bacterial, archaeal, and eukaryotic ribosomes account for the selective action of antibiotics. Even minor variations in the structure of ribosomes of different bacterial species may lead to idiosyncratic, species-specific interactions of the drugs with their targets. Although crystallographic structures of anti...

Alternative Titles

Full title

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_20779932

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_20779932

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1007988107

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