Functional Expression of Mouse mdr1 in Escherichia coli
Functional Expression of Mouse mdr1 in Escherichia coli
About this item
Full title
Author / Creator
EITAN BIBI , GROS, P and KABACK, H. R
Publisher
Washington, DC: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
We describe functional expression of the mouse multidrug-resistance protein (P-glycoprotein; P-gp) in an Escherichia coli mutant defective in the outer membrane protease omp T. Heterologously expressed mdr 1 appears as an unglycosylated species with an apparent molecular mass of 140 kDa in the membrane of the mutant. Unglycosylated mdr1 retains the...
Alternative Titles
Full title
Functional Expression of Mouse mdr1 in Escherichia coli
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_2363116
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_2363116
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.90.19.9209
