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Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by dis...

Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by dis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23749717

Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms

About this item

Full title

Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.16085-16090

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

RNAi-mediated antiviral immunity in Caenorhabditis elegans requires Dicer-related helicase 1 (DRH-1), which encodes the helicase and C-terminal domains homologous to the mammalian retinoic acid inducible gene I (RIG-I)-like helicase (RLH) family of cytosolic immune receptors. Here we show that the antiviral function of DRH-1 requires the RIG-I homo...

Alternative Titles

Full title

Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_23749717

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23749717

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1307453110

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