Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by dis...
Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms
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Author / Creator
Guo, Xunyang , Zhang, Rui , Wang, Jeffrey , Ding, Shou-Wei and Lu, Rui
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
RNAi-mediated antiviral immunity in Caenorhabditis elegans requires Dicer-related helicase 1 (DRH-1), which encodes the helicase and C-terminal domains homologous to the mammalian retinoic acid inducible gene I (RIG-I)-like helicase (RLH) family of cytosolic immune receptors. Here we show that the antiviral function of DRH-1 requires the RIG-I homo...
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Full title
Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms
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Record Identifier
TN_cdi_jstor_primary_23749717
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23749717
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1307453110