Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Parkinson disease (PD) is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta (SNpc). Although growing evidence indicates that endoplasmic reticulum (ER) stress is a hallmark of PD, its exact contribution to the disease process is not well understood. Here we report that developmental ablation of X-Box...
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Full title
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
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TN_cdi_jstor_primary_23772602
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772602
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1321845111