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Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772602

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

About this item

Full title

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6804-6809

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Parkinson disease (PD) is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta (SNpc). Although growing evidence indicates that endoplasmic reticulum (ER) stress is a hallmark of PD, its exact contribution to the disease process is not well understood. Here we report that developmental ablation of X-Box...

Alternative Titles

Full title

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_23772602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772602

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1321845111

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