CRF-CRF₁ system activation mediates withdrawal-induced increases in nicotine self-administration in...
CRF-CRF₁ system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Nicotine, the main psychoactive ingredient of tobacco, induces negative emotional symptoms during abstinence that contribute to a profound craving for nicotine. However, the neurobiological mechanisms underlying how nicotine produces dependence remains poorly understood. We demonstrate one mechanism for both the anxiety-like symptoms of withdrawal...
Alternative Titles
Full title
CRF-CRF₁ system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_25450205
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25450205
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0707585104
