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Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced...

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25450259

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

About this item

Full title

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17471-17476

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Malaria has been a major selective force on the human population, and several erythrocyte polymorphisms have evolved that confer resistance to severe malaria. Plasmodium falciparum rosetting, a parasite virulence phenotype associated with severe malaria, is reduced in blood group O erythrocytes compared with groups A, B, and AB, but the contributio...

Alternative Titles

Full title

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25450259

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25450259

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0705390104

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