Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormon...
Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Blastocyst implantation is a critical stage in the establishment of pregnancy. Leukemia inhibitory factor (LIF) is essential for mouse blastocyst implantation and also plays a role in human pregnancy. We examined the effect of a potent LIF antagonist (LA) on mouse implantation. In mice, LIF expression peaks on day 3.5 of pregnancy (D3.5) (D0.5 = da...
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Full title
Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy
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TN_cdi_jstor_primary_25450714
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25450714
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0710110104